Zydax 100 20ml
This is a prescription medicine. A prescription is required from your veterinarian before we can supply this product. Please ensure that you have read the "How to Order" page before ordering this item.
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|Drug Name and Strength||sodium pentosan polysulfate(100mg/mL)|
|Indication||An aid in the treatment of noninfectious inflammatory joint disease in dogs. Clinical applications include the following conditions: osteoarthritis, osteochondritis dissecans, traumatic joint and periarticular inflammation in working and racing dogs, and following intra-articular surgery.|
|Contraindications||This product is contraindicated for use in dogs with congestive heart disease, severe renal disease, primary hepatic failure or oedema; and in bitches that are pregnant or lactating.|
|Actions||Pentosan polysulfate sodium (PPS) is a semisynthetic polysaccharide with a linear xylan (pentosan) backbone. Xylan is a hemicellulose derived from plant origin. PPS possesses anti-inflammatory, antiarthritic and chondroprotective activities. The beneficial effects of pentosan polysulfate in joint disease are due to the following actions: anti-inflammatory activity; inhibition of neutrophil migration into the joint; stimulation of hyaluronic acid synthesis by synovial fibroblasts, resulting in increased volume and viscosity of synovial fluid; stimulation of proteoglycan synthesis by chondrocytes; and fibrinolytic activity, resulting in improved circulation to subchondral bone and periarticular structures.|
|Precautions||First Aid If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131 126.Disposal Dispose of empty container by wrapping with paper and putting in garbage.|
|Dosage and Administration||Dogs. Pentosan polysulfate sodium 3 mg/kg bodyweight (≡ 1 mL/33 kg) by subcutaneous or intramuscular injection on four occasions with an interval of five to seven days between injections.|
|Storage||Store between 2 and 8°C. (Refrigerate. Do not freeze.) Protect from light. Following withdrawal of first dose, use the remainder of the vial within 28 days or discard the unused portion.|
|MSDS (external link)||Zydax 100 MSDS|
|Label (external link)||Zydax 100 Label|
|Manufacturer||Parnell Australia Pty Ltd|