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|Drug Name and Strength||Stilboestrol 1 mg|
|Indication||Suppression of lactation in bitches and treatment of prostatic carcinoma in dogs. Treatment of hormone responsive incontinence in dogs.|
|Contraindications||Do not use in food producing animals. Do not use in pregnant or lactating animals. Do not use in animals with mammary or bone marrow cancers. Do not use in males that are to be used for breeding. Do not use in cats.|
|Actions||Stilboestrol (also known as diethylstilbestrol) is a type of nonsteroidal oestrogen. It is used for the treatment of urinary incontinence in dogs, prostate hypertrophy (enlargement), certain types of cancers, and reproductive conditions.Hormone responsive incontinence in dogs is common and most often seen in spayed bitches, particularly those spayed before 20 weeks of age.|
|Precautions||Use with caution in animals with liver failure or animals with high levels of liver enzyme induction, e.g. with concurrent use of corticosteroids, anticoagulants, phenobarbital, phenylbutazone, rifampicin, vitamins or supplements. Stilboestrol should not be used to prevent pregnancy due to accidental breeding or mismating in dogs as it is not sufficiently effective.Pregnant women, or women wanting to become pregnant, should not come into contact with the tablets.First Aid If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131 126.|
|Dosage and Administration||Give by oral administration. 0.2 to 5 mg or as directed by a veterinary surgeon. Incontinence. 0.1 to 1 mg daily for three to five days, then 1 mg weekly or as required to maintain continence.The aim of treatment is to provide the lowest possible dose at the longest possible interval. A common course could be 0.1 to 0.3 mg/kg/day orally for seven to 10 days, followed by 1 mg/dog/week. Once a total cumulative dose of 20 mg is reached, therapy should be discontinued for a few months before restarting, to reduce the risk of side effects.In dogs with prostate cancer, doses of up to 1 mg/animal/day have been used for up to 25 weeks in one study, without remission being achieved, but without significant progression of the disease.For treating prostatic hyperplasia in dogs, a typical dose is 0.2 to 1 mg total for five days.|
|Storage||Store below 30°C (room temperature).|
|MSDS (external link)||Stilboestrol Tablets MSDS|
|Label (external link)||Stilboestrol Tablets Label|
|Manufacturer||Apex Laboratories Pty Ltd|