Framixin Ointment 5g

Zinc bacitracin 500 IU/g,
Framycetin sulfate 5 mg/g,
Polymyxin B sulfate 5,000 IU/g
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More Information
Drug Name and StrengthZinc bacitracin 500 IU/g,
Framycetin sulfate 5 mg/g,
Polymyxin B sulfate 5,000 IU/g
Quantity5g Tube
IndicationBacterial infections of the eye or ear in dogs, cats, horses, cattle and sheep.
ActionsFramixin contains three antibiotics to provide a broad spectrum of activity against Gram-negative and Gram-positive bacteria and fungi. Activity against Staphylococci, Streptococci and Pseudomonas is significant. These three antibiotics have good aural activity while there is negligible systemic absorption. Cross resistance between the three is unlikely; however, cross resistance can occur between framycetin and neomycin products.Microbiology The antibacterial spectrum of framycetin includes Staphylococcus sp., Escherichia coli , Klebsiella sp., Haemophilus sp., Proteus sp., Salmonella sp., Shigella sp. and mycobacteria. The antibacterial spectrum of polymyxin includes E. coli , Klebsiella, Haemophilus, Salmonella, Shigella, Pseudomonas, fungi and protozoa. The antibacterial spectrum of bacitracin includes Staphylococcus sp., Streptococcus sp., Clostridium sp., Corynebacterium sp. and Treponema sp.
WarningsCare should be exercised when changing from one aural medication to another because of possible incompatibilities including the following: polymyxin is incompatible with chloramphenicol, cephalosporins, tetracycline, nitrofurans, cloxacillin, kanamycin and prednisolone sodium acetate; framycetin is incompatible with polysorbate and novobiocin; and bacitracin is incompatible with macrogol, propylene glycol, benzalkonium chloride, phenol and tannic acid.
PrecautionsFirst Aid If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131 126.
Dosage and AdministrationSqueeze a small amount into the affected ear at least four times/day for seven days. If the condition has not resolved in seven days, reassessment is recommended.
StorageStore below 25°C (air conditioning).
MSDS (external link)Framixin Ear & Eye Ointment MSDS
Label (external link)Framixin Ear & Eye Ointment Label
ManufacturerApex Laboratories Pty Ltd
Refrigerated ProductNo
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