Cloxacillin 200 mg
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|Drug Name and Strength||Ampicillin 75 mg,|
Cloxacillin 200 mg
|Indication||Treatment of mastitis in lactating cows caused by organisms sensitive to ampicillin and cloxacillin. Its use is particularly recommended where the causative organisms have not been identified and where E. coli is known or suspected to be involved. The best results will be obtained where treatment is commenced at the first signs of infection, before there is too much tissue damage or abscess formation. Mastitis is a herd problem which can only be controlled by disciplined attention to complete control programs.|
|Actions||Broad spectrum antibiotic infusion containing the synthetic penicillins ampicillin and cloxacillin. In combination, ampicillin and cloxacillin have a synergistic action against a range of Gram-positive and Gram-negative bacteria. Cloxacillin is thought to bind to the β-lactamase enzyme and thus prevents the enzyme acting on ampicillin. Ampiclox LC is well distributed within the udder, and shows bactericidal activity at the concentrations achieved in the udder against all major Gram-positive and Gram-negative bacteria associated with mastitis, with no irritant properties. It is highly effective against Streptococci, penicillin resistant and sensitive Staphylococci, Corynebacterium pyogenes, Escherichia coli and other Gram-negative organisms.|
|Precautions||Wear sanitised rubber gloves when applying.|
|Dosage and Administration||Apply 1 syringe to each affected quarter every 12 hours for three treatments. After milking, clean and disinfect the teat with an approved teat disinfectant, and ensure the teat end is dried. Insert the nozzle into the teat canal and apply gentle and continuous pressure on the plunger until all the suspension is expressed. Dip all teats with an approved teat disinfectant after infusion.|
|Storage||Store below 25°C (air conditioning).|
|MSDS (external link)||Ampiclox L.C. MSDS|
|Label (external link)||Ampiclox L.C. Label|
|Manufacturer||Jurox Pty Limited|